Thank you for the suggestion. I ran the purge bat file as suggested and re-ran setup, but unfortunately the problem still exists.
Upon doing a little more research the problem appears to be related to the installation location of the setting content files and the start10 search function. For this new installation the control panel files are placed in the following location:
C:\Users\USERNAME\Start10Ctrlpnl\
I have another Windows 10 machine that I installed Start10 on a while ago and the control panel files are in the following location:
C:\Users\USERNAME\AppData\Local\Packages\windows.immersivecontrolpanel_cw5n1h2txyewy\LocalState\Indexed\Settings\en-US
On the working machine if I use the start10 search box it finds the location of the control panel files and launches successfully.
On the non-working machine I copied the control panel files to C:\Users\USERNAME\AppData\Local\Packages\windows.immersivecontrolpanel_cw5n1h2txyewy\LocalState\Indexed\Settings\en-US and I am able to launch the control panel applets successfully, however, the start10 search box still returns search results for the applets in the location where they cannot be run from.
I also noticed that if I use the Cortana search I am able to launch the various control panel applets successfully. It is only when using the normal start10 search function which points to the C:\Users\USERNAME\Start10Ctrlpnl\ location that fails. As far as permissions are concerned I tried everything on that folder including taking ownership, setting full control permissions explicitly, and creating a new folder with the applets in it.
I didn't get any prompt during installation as to where to install these files.
Thanks!